Advanced Pharmacotherapy in Critical Care Online-Halting the Domino Effect: Preventing and Managing Iatrogenic Withdrawal Syndrome (Scott Bolesta, PharmD, BCCCP, FCCP, FCCM)

Halting the Domino Effect: Preventing and Managing Iatrogenic Withdrawal Syndrome (Scott Bolesta, PharmD, BCCCP, FCCP, FCCM)

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Video Transcription

Video Summary

The video transcript discusses iatrogenic withdrawal syndrome, focusing on its prevalence, impact on patient outcomes, strategies to mitigate it through pharmacologic and non-pharmacologic modalities, and the utility of clinical scoring tools for assessment. In the pediatric ICU population, tools like the Withdrawal Assessment Tool 1 and the SOFIA Observation Symptom Scale are validated for assessing iatrogenic withdrawal. However, in the adult ICU population, there are no validated tools available. Studies have explored the use of medications like methadone and clonidine for weaning opioids and sedatives, and protocols for weaning have shown benefits in reducing the occurrence of iatrogenic withdrawal. The guidelines recommend standardized protocols for weaning in the PICU and emphasize the need for further research in the adult ICU population. Overall, the importance of standardized approaches and validated tools for assessing and managing iatrogenic withdrawal is highlighted throughout the transcript.

Keywords

iatrogenic withdrawal syndrome

pediatric ICU population

pharmacologic modalities

non-pharmacologic modalities

Withdrawal Assessment Tool 1

SOFIA Observation Symptom Scale

methadone

clonidine

weaning protocols

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