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Advanced Pharmacotherapy in Critical Care Online
Hitting the Target: Therapeutic Drug Monitoring fo ...
Hitting the Target: Therapeutic Drug Monitoring for Beta-Lactam Antibiotics in the Critically Ill (Lauren Andrews, PharmD, BCCCP)
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Video Summary
Lauren Andrews presented "Hitting the Target: Therapeutic Drug Monitoring for Beta-Lactam Antibiotics in the Critically Ill" as part of SECM's 2024 Advanced Pharmacology course. The presentation highlighted the importance of optimizing beta-lactam antibiotic levels in critically ill patients through therapeutic drug monitoring (TDM) to improve clinical outcomes and prevent antibiotic resistance. Studies have shown variability in beta-lactam concentrations in critically ill patients, emphasizing the need for individualized dosing strategies. TDM can help achieve pharmacodynamic targets and decrease the risk of toxicities. Challenges in implementing beta-lactam TDM in medical centers include the lack of standardized guidelines, limited diagnostic laboratories, and variability in dosing recommendations. The presentation emphasized the importance of personalized dosing to improve patient outcomes and encouraged clinicians to address barriers in their institutions to optimize antibiotic therapy for critically ill patients.
Keywords
Lauren Andrews
Therapeutic Drug Monitoring
Beta-Lactam Antibiotics
Critically Ill
Pharmacology
Clinical Outcomes
Personalized Dosing
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