Current Concepts in Pediatric Critical Care-2: Neuroprotective Strategies

Video Transcription

Video Summary

Dr. Balala, a pediatric intensivist, discusses neuroprotective strategies in the context of neuroinjury in children, specifically focusing on traumatic and non-traumatic injuries. He explains that secondary neuronal injury occurs through mechanisms such as excitotoxicity, oxidative stress, endotheliopathy, and neuroinflammation. Dr. Balala then discusses conventional neuroprotective strategies, which include tight control of temperature, oxygen, carbon dioxide, glucose, sodium, and seizure prevention and management. He mentions that hyperoxia and hypocapnia should be avoided, and maintaining normal arterial carbon dioxide levels is recommended. Additionally, he suggests maintaining blood pressure above the fifth percentile for age, avoiding hyperglycemia and hyponatremia, and managing seizures according to American Academy of Neurology guidelines. Finally, Dr. Balala discusses targeted temperature management, explaining that therapeutic hypothermia or normothermia can be used depending on the patient's age and the type of cardiac arrest. He emphasizes the importance of early initiation and closely monitoring the patient's physiologic parameters during the cooling or normothermia period.

Asset Caption

Utpal Bhalala, MD, FCCM

Keywords

neuroprotective strategies

secondary neuronal injury

therapeutic hypothermia

pediatric neuroinjury

seizure management

physiologic monitoring

	Society of Critical Care Medicine 500 Midway Drive Mount Prospect, IL 60056 USA Phone: +1 847 827-6888 Fax: +1 847 439-7226 Email: support@sccm.org	Contact Us About SCCM Newsroom Advertising & Sponsorship DONATE	MySCCM LearnICU Patients & Families Surviving Sepsis Campaign Critical Care Societies Collaborative	GET OUR NEWSLETTER
© Society of Critical Care Medicine. All rights reserved. \| Privacy Statement \| Terms & Conditions The Society of Critical Care Medicine, SCCM, and Critical Care Congress are registered trademarks of the Society of Critical Care Medicine.