Deep Dive: Acute Kidney Injury and Organ Crosstalk Online-Cardiorenal Syndrome: How to Optimize Management

Video Transcription

Video Summary

In this video transcript, Dr. Pranav Garimella, a nephrologist, provides an overview of cardio-renal syndromes, focusing on the interaction between heart failure and kidney function. He discusses the complexity of defining cardio-renal syndromes and the evolution of understanding over the last few decades. Dr. Garimella emphasizes the importance of assessing diuretic response, using biomarkers like urine sodium, and multi-segment nephron blockade to improve outcomes in patients with heart failure. He highlights the challenges of diuretic resistance, distal tubule remodeling, and the potential benefits of targeted therapies like acetazolamide and thiazides. The discussion also delves into the impact of medications like ACE inhibitors and beta blockers on mortality and the importance of continuing these therapies in appropriate patients. Dr. Garimella concludes by emphasizing the need for goal-directed therapy and optimization of treatment strategies for patients with cardio-renal syndromes.

Keywords

cardio-renal syndromes

heart failure

biomarkers

diuretic response

nephron blockade

acetazolamide

goal-directed therapy

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