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OasisLMS
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Deep Dive: Saving the Kidneys
AKI Biomarkers: A New Way to Use Tools You Have
AKI Biomarkers: A New Way to Use Tools You Have
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Video Transcription
Video Summary
The speaker discussed the use of readily available biomarkers in the diagnosis and care of patients with acute kidney injury (AKI). They emphasized the heterogeneity of AKI and the need to improve diagnostic precision. The speaker highlighted the importance of urine output as a biomarker, as it captures a subset of patients missed by serum creatinine alone and identifies patients with worse outcomes. They also mentioned the use of the furosemide stress test (FST) as a cheap and easy way to assess tubular function early on in AKI patients. The FST accurately predicts AKI progression in adults, but more prospective studies are needed in pediatric patients. The speaker also discussed the use of fluid overload as a biomarker, which can identify high-risk AKI sub-phenotypes. Furthermore, they highlighted the importance of considering the kinetics of serum creatinine and the duration and severity of AKI in prognostication. The speaker concluded by providing a framework for risk stratification and management of AKI patients based on these biomarkers.
Asset Caption
Natalja L. Stanski
Keywords
acute kidney injury
urine output
furosemide stress test
fluid overload
biomarkers
prognostication
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