ICU Management of HRS/AKI and Multiorgan Failure in Patients With Decompensating Cirrhosis-Part 1

Video Transcription

Video Summary

Dean Karvelas presented on managing acute kidney injury and multi-organ failure in patients with decompensated cirrhosis. He discussed the importance of defining ACLF and its high mortality rate without liver transplant. Karvelas highlighted the CLIF-ACLF score for prognosis assessment and emphasized the impact of acute kidney injury on mortality in ACLF. He delved into circulatory management, respiratory failure causes, variceal bleeding interventions, and hepatic encephalopathy treatments. Karvelas shared insights on renal replacement therapy, emphasizing the safety of initiating continuous modes in unstable patients. He discussed preoperative conditioning for liver transplant recipients and the potential benefits of intraoperative CRRT. Lastly, he touched on the resource-intensive nature of transplanting high-risk ACLF patients and the need for personalized management strategies in this challenging population.

Keywords

acute kidney injury

multi-organ failure

decompensated cirrhosis

ACLF

CLIF-ACLF score

renal replacement therapy

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