ICU Management of HRS/AKI and Multiorgan Failure in Patients With Decompensating Cirrhosis-Part 2

Video Transcription

Video Summary

In the video, the speaker discusses the etiologies, diagnostic criteria, and management of Acute Kidney Injury (AKI) in patients with cirrhosis or acute-on-chronic liver failure (ACLF). They highlight the importance of understanding various causes of AKI, including Hepatorenal Syndrome (HRS), and the evolving diagnostic criteria, emphasizing the shift towards earlier detection and therapy initiation. The speaker elaborates on the prognostic significance of different stages of HRS AKI and the impact on patient outcomes. They also mention the role of biomarkers like urinary NGAL in predicting response to therapy. The video concludes by emphasizing the complexity of managing AKI in cirrhotic patients with underlying Chronic Kidney Disease (CKD) and the considerations for appropriate treatment strategies, including the potential need for combined liver-kidney transplant in specific cases.

Keywords

Acute Kidney Injury

Cirrhosis

Acute-on-chronic liver failure

Hepatorenal Syndrome

Chronic Kidney Disease

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