Multiprofessional Critical Care Review: Adult (2023)-1: Evidenced-Based Management of Septic Shock (Greg Martin, MD, MS, FCCM)

Video Transcription

Video Summary

In this video, Dr. Greg Martin discusses the evidence-based management of sepsis and septic shock. He defines sepsis as a dysregulated host immune response to infection and explains that sepsis is more complex than just the immune response or the SIRS criteria. He describes the historical perspective of sepsis and the original 1992 consensus clinical definition, which included the systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction. He then explains the sepsis 3 definition, which includes life-threatening organ dysfunction caused by a dysregulated host response to infection, and the criteria for diagnosing sepsis and septic shock, which include organ dysfunction and hypotension despite adequate fluid resuscitation. Dr. Martin also discusses the management strategies for sepsis, including administering antibiotics, fluid resuscitation, vasopressors, and supportive therapies. He emphasizes the importance of early treatment and the goal of normalizing lactate levels through hemodynamic resuscitation. Dr. Martin concludes by highlighting the global burden of sepsis and the need for early diagnosis and management to reduce morbidity and mortality.

Keywords

sepsis

septic shock

evidence-based management

immune response

SIRS criteria

organ dysfunction

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