Multiprofessional Critical Care Review: Adult (2023)-4: Bleeding and Coagulation Disorders: What Am I to Do with Those New Agents? (Janice Zimmerman, MD, MCCM, MACP)

4: Bleeding and Coagulation Disorders: What Am I to Do with Those New Agents? (Janice Zimmerman, MD, MCCM, MACP)

Video Transcription

Video Summary

The video presentation discusses bleeding and coagulation disorders. The speaker emphasizes the importance of identifying the underlying defect before reaching for lab results. They suggest considering the patient's history, clinical signs, and other medical conditions to guide diagnosis. Various lab tests such as platelet count, prothrombin time, partial thromboplastin time, and D-dimer are discussed as ways to assess platelet function and coagulation cascade. The speaker also touches on viscoelastic assays like thromboelastography, which provide a global picture of coagulation and can guide transfusion decisions. Specific disorders such as thrombotic thrombocytopenic purpura, immune thrombocytopenia, disseminated intravascular coagulation, heparin-induced thrombocytopenia, and von Willebrand disease are discussed. The speaker also provides information on managing bleeding in patients taking antiplatelet agents, warfarin, and direct oral anticoagulants. They discuss treatment options such as platelet transfusion, fresh frozen plasma, prothrombin complex concentrate, and specific reversal agents for certain anticoagulants. The speaker concludes by highlighting the need to tailor treatment to each patient's specific circumstances and needs.

Keywords

bleeding disorders

coagulation disorders

platelet function

viscoelastic assays

thrombotic thrombocytopenic purpura

anticoagulants

bleeding management

tailored treatment

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