Multiprofessional Critical Care Review: Adult 2024 (MCCRCA24ON)-07

07_Bleeding Coagulation Disorders

Pdf Summary

The document provides a comprehensive overview of bleeding and coagulation disorders in the critical care setting, emphasizing causes, diagnostic tests, and management strategies. It covers topics ranging from history and examination findings to specific disorders like thrombocytopenia, immune thrombocytopenia, thrombotic thrombocytopenic purpura, and heparin-induced thrombocytopenia. The text discusses the testing protocols including CBC, PT/INR, aPTT, and specific treatment options such as platelet transfusion and factor concentrates. Various conditions like DIC, HIT, von Willebrand disease, hemophilias, and warfarin-related bleeding are also addressed. Management strategies for different scenarios, including trauma-induced coagulopathy and massive transfusion, are outlined. The reversal of antiplatelet agents and bleeding associated with specific drugs like dabigatran and Factor Xa inhibitors are highlighted. Lastly, the document mentions the importance of individualized treatment based on the underlying condition and patient's clinical status while also suggesting potential future advancements in the field.

Keywords

bleeding disorders

coagulation disorders

critical care

diagnostic tests

management strategies

thrombocytopenia

DIC

hemophilias

antiplatelet agents

individualized treatment

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