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Multiprofessional Critical Care Review: Adult 2024 ...
16_Toxicology and Drug Overdoses
16_Toxicology and Drug Overdoses
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Pdf Summary
The document discusses toxicology and drug overdoses in critical care settings, providing guidance on history-taking, physical examination, evaluation, acute management, and specific toxic syndromes. Key points include the importance of scene safety, conducting a thorough physical exam, assessing cardiac and respiratory effects, and utilizing antidotes or supportive care when managing toxic ingestions. The text also presents case scenarios with relevant symptoms and lab findings to highlight differential diagnoses and management strategies for various toxins, such as cholinergic excess and toxic alcohols. Treatment modalities for toxic alcohols include inhibition of metabolism with fomepizole and removal through hemodialysis. Additionally, the document touches on the recognition and treatment of salicylate toxicity, metabolic acidosis causes, and therapeutic adjuncts for managing overdose complications like arrhythmias, hypotension, and seizures. Overall, the content emphasizes the importance of prompt recognition, appropriate interventions, and a systematic approach to treating toxic exposures in critical care settings.
Keywords
toxicology
drug overdoses
critical care
acute management
toxic syndromes
antidotes
toxic alcohols
salicylate toxicity
metabolic acidosis
hemodialysis
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