Multiprofessional Critical Care Review: Pediatric 2024 (MCCRCP24ON)-20

20_Infectious Diseases and Antimicrobials

Pdf Summary

The document discusses the management of infectious diseases and antimicrobial agents in the Pediatric Intensive Care Unit (PICU). It covers the etiologies and clinical manifestations of life-threatening infections, appropriate antimicrobial selection criteria, and strategies to combat antibiotic misuse. The presentation emphasizes the importance of choosing antibiotics based on suspected pathogens, site of infection, and patient-specific factors like age and immune status. It also addresses multidrug-resistant organisms, geographic variations in antimicrobial resistance, and the role of antimicrobial stewardship programs in reducing antibiotic misuse. Additionally, the document includes case scenarios involving meningitis and toxic shock syndrome, detailing empiric antibiotic regimens and management strategies. It highlights the significance of early and appropriate antibiotic therapy in cases of bacterial co-infections with influenza, particularly emphasizing MRSA coverage. Overall, the document stresses the need for a thoughtful and tailored approach to antibiotic therapy in critically ill children, considering various factors to ensure effective treatment while minimizing unnecessary antibiotic use.

Keywords

infectious diseases

antimicrobial agents

Pediatric Intensive Care Unit

life-threatening infections

antibiotic selection

antibiotic misuse

multidrug-resistant organisms

antimicrobial stewardship

meningitis

toxic shock syndrome

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