Multiprofessional Critical Care Review: Pediatric 2024 (MCCRCP24ON)-26

26_Neuromuscular Diseases

Pdf Summary

The document discusses various neuromuscular diseases such as Guillain-Barre Syndrome, Myasthenia Gravis, and Duchenne Muscular Dystrophy, as well as conditions like Botulism, Tick Paralysis, and Tetanus. It focuses on respiratory failure due to muscle weakness, alterations in respiratory mechanics, and the management of respiratory muscle weakness. The text also covers the use of neuromuscular blockers, organophosphates poisoning, and metabolic myopathies like Periodic Paralysis. Additionally, it highlights the importance of diagnosing and treating these conditions promptly, as well as recognizing the potential complications that can arise, such as critical illness neuropathy/myopathy. Key takeaways include thinking anatomically, localizing lesions, and considering similar entities when diagnosing neuromuscular diseases. Guillain-Barre Syndrome may present with symptoms like areflexia and respiratory muscle weakness, while Myasthenia Gravis treatment options include cholinesterase-inhibitors and steroids. Additionally, the document provides insight into cholinergic crisis symptoms, the Tensilon test for myasthenia gravis, and the management of organophosphate poisoning.

Keywords

neuromuscular diseases

Guillain-Barre Syndrome

Myasthenia Gravis

Duchenne Muscular Dystrophy

respiratory failure

neuromuscular blockers

organophosphate poisoning

Periodic Paralysis

critical illness neuropathy

Tensilon test

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