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31_Algorithms for Metabolic Rheumatoloigic
31_Algorithms for Metabolic Rheumatoloigic
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Pdf Summary
The document discusses Inborn Errors of Metabolism (IEM) and Rheumatological Diseases, focusing on various disorders, clinical manifestations, laboratory findings, and management strategies. It outlines different disorders within protein metabolism, fatty acid oxidation, carbohydrate disorders, and more. Specific disorders like Urea Cycle Defects and Organic Acidemias are highlighted, detailing their clinical presentations and diagnostic approaches. Management options, such as hemodialysis and essential amino acid supplementation, are provided. The presentation also delves into Rheumatological Diseases like Systemic Lupus Erythematosus (SLE) and Systemic Juvenile Idiopathic Arthritis (sJIA), discussing their clinical features, diagnostic methods, and treatment strategies. It covers conditions like vasculitis and primary CNS vasculitis, emphasizing the importance of laboratory tests and immunosuppressive therapies. Various case studies are presented to illustrate diagnostic challenges and appropriate management approaches, including the importance of newborn screening in detecting metabolic disorders early. Lastly, it provides interactive questions to test knowledge on the topics covered, such as identifying the most likely diagnosis based on laboratory findings and selecting appropriate dietary interventions for specific conditions like Galactosemia.
Keywords
Inborn Errors of Metabolism
Rheumatological Diseases
Urea Cycle Defects
Organic Acidemias
Systemic Lupus Erythematosus
Systemic Juvenile Idiopathic Arthritis
vasculitis
newborn screening
diagnostic challenges
management strategies
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