Neurocritical Care Review Course-Hematology

Video Transcription

Video Summary

In this video, Dr. Rhonda Kadena discusses high-yield hematology topics relevant to the Neurocritical Care Boards. She addresses various neurological complications related to hematological disorders, chemotherapy, stem cell transplantation, and CAR T therapy. Dr. Kadena starts by discussing anemia and the risks associated with transfusions, emphasizing the importance of determining the cause of anemia and understanding transfusion goals. She then explains the different types of anemia based on red blood cell volume and mechanisms of intrinsic anemia. Hemolysis, the destruction of red blood cells, is also discussed, including its mechanisms and associated laboratory findings. Dr. Kadena highlights the oxygen delivery equation and its importance in neurocritical care. Coagulopathies and their role in neuro-ICU complications are reviewed, specifically focusing on bleeding and prothrombotic coagulopathies. Thrombotic microangiopathies, such as TTP and HUS, are described, including their clinical presentations and treatment options. Dr. Kadena further discusses thrombocytopenia, DIC, and HIT, providing insights into their causes, diagnostic tests, and management strategies. Oral anticoagulants and their reversal options are also covered. Lastly, neurological complications of sickle cell disease, stem cell transplantation, and CAR T therapy are explained.

Asset Caption

Rhonda S. Cadena, MD, FCCM

Keywords

high-yield hematology

neurological complications

hematological disorders

chemotherapy

stem cell transplantation

CAR T therapy

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