Neurocritical Care Review Course-Neuroinfections/Neuroinflammatory Disease I

Video Transcription

Video Summary

In this lecture on neuroinfections, Dr. Shweta Mainali discusses the common bacterial, viral, and fungal pathogens involved in central nervous system (CNS) infections. Meningitis is defined as inflammation of the leptomeninges without involvement of the brain parenchyma, while encephalitis is characterized by cognitive impairment, motor/sensory deficits, and behavior/personality changes. Diagnostic criteria for encephalitis include altered mental status lasting greater than or equal to 24 hours, along with other minor criteria. Common causes of meningitis include bacterial, viral, and fungal pathogens, with strep pneumoniae and nesseria meningitidis being the most common bacterial pathogens in adults. Treatment of bacterial meningitis involves early initiation of empiric antimicrobial therapy, while fungal meningitis requires antifungal therapy. Viral meningitis is often self-limited, and management focuses on supportive care. Other topics covered in the lecture include spinal epidural abscesses, herpes encephalitis, cerebral abscesses, and ventriculitis.

Asset Caption

Shraddha Mainali, MD

Keywords

neuroinfections

bacterial pathogens

viral pathogens

fungal pathogens

meningitis

encephalitis

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