SCCM Resource Library-Achieving Targeted Vancomycin Levels in Augmented Renal Clearance

Achieving Targeted Vancomycin Levels in Augmented Renal Clearance

Video Transcription

Video Summary

The researcher, Sydney Wilson, discusses the evaluation of achieving targeted vancomycin levels in patients with augmented renal clearance (ARC). ARC is defined as a creatinine clearance greater than 130 mL/min/m², which is observed in 30-65% of ICU patients. The study aims to analyze the results of research on vancomycin use in patients with ARC and evaluate St. Luke's Health System's current vancomycin dosing protocol. The study found that 57% of patients achieved an initial therapeutic trough level, with higher ARC scores associated with lower odds of achieving therapeutic levels. The study suggests adjustments to the dosing protocol based on patient age, weight, and creatinine clearance.

Asset Subtitle

Pharmacology, 2023

Asset Caption

Type: star research | Star Research Presentations: Infectious Disease (SessionID 30012)

Meta Tag

Content Type Presentation

Knowledge Area Pharmacology

Membership Level Professional

Membership Level Select

Tag Antibiotics

Year 2023

Keywords

ARC

vancomycin levels

dosing protocol

therapeutic trough level

creatinine clearance

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