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Adaptive Immune Function and Immunoparalysis in Ch ...
Adaptive Immune Function and Immunoparalysis in Children With Septic Shock
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Video Transcription
Video Summary
Diego Cruz, a Pediatric Infectious Disease Fellow at Nationwide Children's Hospital, discusses the concept of immune paralysis in children with septic shock, focusing on both the innate and adaptive immune responses. He explains that immune paralysis is associated with adverse outcomes in septic children and highlights the need to understand biomarkers of lymphocyte function in this setting. Through their study, they found that septic children with immune paralysis had a suppression of both the innate and adaptive immune response. This information could be used to identify patients for future clinical trials of immunomodulatory therapies and as biomarkers of immune function recovery.
Asset Subtitle
Sepsis, Pediatrics, 2023
Asset Caption
Type: star research | Star Research Presentations: Biomarkers II, Pediatrics (SessionID 30008)
Meta Tag
Content Type
Presentation
Knowledge Area
Sepsis
Knowledge Area
Pediatrics
Membership Level
Professional
Membership Level
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Tag
Pediatrics
Tag
Shock
Year
2023
Keywords
immune paralysis
septic shock
innate immune response
adaptive immune response
biomarkers of lymphocyte function
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