SCCM Resource Library-Antibiotics, Enzymes, and Powders: Managing the Magic of Pharmacologic Agents Used in Complex Wounds

Video Transcription

Video Summary

In this video, Leslie Hamilton, an associate professor and pharmacist, discusses the use of antibiotics, enzymes, and powders in managing complex wounds. She highlights the increasing concern of antibiotic resistance and the need for judicious use of antimicrobials. Factors that contribute to antibiotic resistance include diagnostic uncertainty, clinician inexperience, clinician fear, and patient demand for antibiotics. Hamilton emphasizes the importance of considering the type of infection and the organisms likely to grow when selecting antimicrobials. She provides a flowchart for determining whether a wound is infected and when to use systemic antibiotics. Hamilton also discusses the use of topical antibiotics, such as fucidic acid and mupirocin, and topical antiseptics, such as chlorhexidine and povidone iodine. She presents data from studies comparing oral versus IV antibiotics for bone and joint infections and the duration of antibiotics for diabetic foot osteomyelitis. Overall, Hamilton emphasizes the need for antimicrobial stewardship to prevent drug resistance and preserve treatment options.

Asset Subtitle

Integument, Quality and Patient Safety, 2022

Asset Caption

With the increased acuity and aging of the critical care population and the multiple comorbidities associated with specialty conditions, the incidence of catastrophic wounds has significantly increased. Many of these wounds may be preventable and managed earlier. This session will highlight the unique situations in which these wounds develop—whether they are caused by pressure ulcers, unique infectious diseases, pharmaceutical reactions, or oncologic conditions—how critical care professionals can identify their causes, and ways to identify and manage them to successful outcomes.

Meta Tag

Content Type Presentation

Knowledge Area Integument

Knowledge Area Quality and Patient Safety

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Wound Healing

Tag Evidence Based Medicine

Year 2022

Keywords

antibiotic resistance

antimicrobials

topical antibiotics

systemic antibiotics

antimicrobial stewardship

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