SCCM Resource Library-Antipsychotics and QTc Interval in the ICU: Analysis of a Randomized Clinical Trial

Antipsychotics and QTc Interval in the ICU: Analysis of a Randomized Clinical Trial

Video Transcription

Video Summary

The study presented by the speaker aimed to investigate the influence of antipsychotic medications on the change in QTC interval in critically ill patients with delirium. The study included 566 patients who were randomized to receive either haloperidol, ziprasidone, or placebo. The researchers found that neither haloperidol nor ziprasidone significantly affected the QTC interval. They also found no association between antipsychotic administration and ventricular arrhythmias. The study concluded that the frequency of QTC monitoring may be excessive in such patients. Overall, the study suggests that antipsychotics do not have a significant impact on QTC intervals in critically ill patients with delirium.

Asset Subtitle

Research, Pharmacology, 2023

Asset Caption

Type: star research | Star Research Presentations: Pharmacology I (SessionID 30015)

Meta Tag

Content Type Presentation

Knowledge Area Research

Knowledge Area Pharmacology

Membership Level Professional

Membership Level Select

Tag Outcomes Research

Tag Psychopharmacology

Year 2023

Keywords

antipsychotic medications

QTC interval change

critically ill patients

delirium

QTC monitoring

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