SCCM Resource Library-August Journal Club Webcast: Spotlight on Pharmacy (2021)

Video Transcription

Video Summary

Today's Journal Club Spotlight on Pharmacy webcast discussed the optimal sedation in patients with acute respiratory distress syndrome (ARDS) and the use of neuromuscular blocking agents (NMBAs) for treatment. The first presenter discussed a study that looked at the use of paralysis in patients with ARDS. They highlighted the ACURISIS trial, which found that paralysis improved 90-day survival in patients with severe ARDS. However, the ROSE trial showed no reduction in mortality with paralysis and an increased incidence of adverse events. The second presenter focused on a study that investigated the use of nebulized heparin in patients at risk for ARDS. The study found that nebulized heparin did not improve functional independence at 60 days compared to placebo. The third presenter discussed the effect of endovascular treatment alone versus IV alteplase plus endovascular treatment in patients with acute ischemic stroke. The DEPTH Trial found that endovascular treatment alone was not inferior to combination therapy with alteplase and endovascular treatment in terms of functional independence at 90 days. Overall, these studies provide insights into optimal sedation and treatment strategies for patients with ARDS and acute ischemic stroke.

Asset Subtitle

Pharmacology, Pulmonary, 2021

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Pulmonary

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Analgesia and Sedation

Tag Acute Respiratory Distress Syndrome ARDS

Year 2021

Keywords

sedation

acute respiratory distress syndrome

ARDS

neuromuscular blocking agents

ACURISIS trial

ROSE trial

mortality

nebulized heparin

functional independence

endovascular treatment

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