SCCM Resource Library-Can We Use Biomarkers to Better Understand Neurologic Injury in Pediatric ECMO?

Can We Use Biomarkers to Better Understand Neurologic Injury in Pediatric ECMO?

Video Transcription

Video Summary

The presentation discusses a study on the use of biomarkers to understand brain injury in children undergoing ECMO (Extracorporeal Membrane Oxygenation). The study, funded for five years and involving 11 centers, explores neuroimaging and plasma biomarkers to diagnose injuries and predict outcomes. Acute neurologic injuries occur in a significant percentage of ECMO patients, potentially leading to increased mortality and long-term disabilities. This research aims to develop effective, minimally invasive diagnostic measures, focusing on neuroinflammation as a mechanism for injury, and assess long-term neurodevelopmental outcomes in this patient group. Enrollment faced delays due to the pandemic but has now been completed.

Asset Caption

One-Hour Concurrent Session | Can We Improve Outcomes in Pediatric ECMO With Clinical Research?

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

biomarkers

ECMO

neuroimaging

neuroinflammation

neurodevelopmental outcomes

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