SCCM Resource Library-Choosing the Right Drug

Video Transcription

Video Summary

The video discusses the topic of pharmacotherapy for pulmonary arterial hypertension (PAH) in critically ill patients. The presenter focuses on how to manage PAH patients who are already on multiple medications and are admitted to the ICU. The different classes of drugs used to treat PAH include prostacyclin pathway drugs, endothelin pathway drugs, and nitric oxide pathway drugs. The prostacyclin pathway drugs increase prostacyclin levels, which helps with vasodilation and antiproliferation. The endothelin pathway drugs target endothelin receptors to prevent vasoconstriction. The nitric oxide pathway drugs help increase nitric oxide levels, which leads to vasodilation. The presenter discusses different strategies for managing PAH medications in the ICU, including converting subcutaneous prostacyclin drugs to intravenous ones, administering inhaled pulmonary vasodilators, and transitioning oral medications to different routes. The video concludes by summarizing the various strategies available to healthcare providers for managing PAH medications in critically ill patients.

Asset Subtitle

Pharmacology, 2023

Asset Caption

Type: one-hour concurrent | The People's Ventricle (SessionID 1333302)

Meta Tag

Content Type Presentation

Knowledge Area Pharmacology

Membership Level Professional

Membership Level Select

Tag Pharmacology

Year 2023

Keywords

pharmacotherapy

pulmonary arterial hypertension

critically ill patients

ICU

prostacyclin pathway drugs

endothelin pathway drugs

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