SCCM Resource Library-Clinical Trial Design During the COVID-19 Pandemic: Traditional Versus Adaptive Designs: Is There a Winner?

Clinical Trial Design During the COVID-19 Pandemic: Traditional Versus Adaptive Designs: Is There a Winner?

Video Transcription

Video Summary

In this video, Dr. John Stavransky discusses the challenges of conducting clinical trials during the COVID-19 pandemic. He explains the differences between frequentist and adaptive trial designs and highlights their advantages and disadvantages. Frequentist trials are more familiar and have been widely used in the past, but they can be inefficient and may not allow for testing multiple hypotheses. On the other hand, adaptive designs are more flexible and efficient, allowing for modifications based on patient outcomes. While there have been more frequentist trials published, Dr. Stavransky suggests that adaptive trials may become more common in the future.

Asset Subtitle

Infection, Research, 2022

Asset Caption

This year in review on behalf of SCCM's Research Section will focus on three timely subtopics: research design strategies during a pandemic, the role of preprint servers, and strategies for interacting with the media.

Meta Tag

Content Type Presentation

Knowledge Area Infection

Knowledge Area Research

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Clinical Research Design

Tag COVID-19

Year 2022

Keywords

clinical trials

COVID-19 pandemic

frequentist trial designs

adaptive trial designs

advantages and disadvantages

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