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Video Summary
The speaker presents the pro-targeted temperature management (TTM) position, arguing that induced hypothermia is not dead yet. They highlight several unanswered questions in the existing literature, including the fact that many studies do not reflect the populations of cardiac arrest patients that are actually cared for, especially in the US. They also suggest that patients with more severe hypoxic ischemic brain injury may benefit from a lower temperature goal, and that completely abandoning induced hypothermia could disrupt the post-arrest bundle and potentially worsen outcomes. They discuss the TTM-2 trial, which showed no significant difference in outcomes between different temperature goals, but also note that the trial population may not be representative. They also mention the Hyperion trial, which showed a benefit for cooling to 33 degrees Celsius in patients with non-shockable initial rhythms. The speaker suggests that ongoing trials, such as ICECAP, may provide further insights into the efficacy of TTM. They conclude by expressing concern that abandoning induced hypothermia may lead to premature decisions about withdrawing life-sustaining therapy and emphasize the importance of the post-arrest bundle and neurologic prognostication.
Asset Subtitle
Professional Development and Education, 2023
Asset Caption
Type: one-hour concurrent | Pro/Con: Targeted Temperature Management Post-Cardiac Arrest Is Pointless: Change My Mind (SessionID 1120534)
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Presentation
Knowledge Area
Professional Development and Education
Membership Level
Professional
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Tag
Professional Development
Year
2023
Keywords
pro-targeted temperature management
induced hypothermia
cardiac arrest patients
severe hypoxic ischemic brain injury
post-arrest bundle
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