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Creatinine and Its Influence on Racial Disparities
Creatinine and Its Influence on Racial Disparities
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Video Summary
Dr. Christian Bimi, a pulmonary critical care doctor, emphasizes the limitations of using race-based equations to estimate kidney function in the ICU. Traditionally, renal function has been assessed through glomerular filtration rate (GFR) using creatinine levels, often adjusted for race, which has introduced inaccuracies and biases. Research indicated race-based adjustments, initially justified by unverified assumptions, inaccurately estimated GFR for black patients, impacting medical decisions like drug dosing and dialysis initiation. Recent studies advocate replacing race-based equations with biomarkers like cystatin C, which offer more accurate, race-agnostic estimates. These findings highlight the necessity to develop and adopt formulas that reflect diverse population data and rely on more precise biomarkers. Overall, eliminating race adjustment and incorporating more comprehensive biomarkers promise better accuracy and equity in estimating kidney function.
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One-Hour Concurrent Session | Free Your Mind: Sources of Systematic Bias in the ICU
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Presentation
Membership Level
Professional
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Year
2024
Keywords
race-based equations
kidney function
glomerular filtration rate
cystatin C
biomarkers
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