SCCM Resource Library-Emerging Issues in Toxicology

Video Transcription

Video Summary

The video transcript discusses the emerging issue of toxicities associated with alternative analgesics, specifically tramadol and gabapentin. These alternative analgesics have been increasingly used as alternatives to traditional opioids in the ongoing opioid epidemic. The transcript highlights the increase in prescriptions for tramadol and gabapentin and the corresponding increase in toxicity associated with their use. Tramadol, a synthetic opioid, has been touted as a safer alternative to traditional opioids, but it is shown to have significant toxicities including respiratory depression, seizures, and serotonin syndrome. Gabapentin, an antiepileptic drug, is also being used as an alternative analgesic and is associated with sedation, dizziness, and an increased risk of opioid-related deaths when co-prescribed with opioids. The transcript also briefly mentions other emerging toxicities associated with alternative analgesics, including those associated with antidepressants and NSAIDs. Overall, the transcript emphasizes the need for careful consideration of the risks and benefits of alternative analgesics and the importance of monitoring and managing the toxicities associated with their use.

Asset Subtitle

Pharmacology, Crisis Management, 2021

Asset Caption

The Society of Critical Care Medicine's Critical Care Congress features internationally renowned faculty and content sessions highlighting the most up-to-date, evidence-based developments in critical care medicine. This is a presentation from the 2021 Critical Care Congress held virtually from January 31-February 12, 2021.

Learning Objectives

Identify causative agents and underlying pathophysiology and discuss the importance of coordinated public health response in toxic surveillance
Discuss toxicities of analgesics that are being more commonly used as alternatives to traditional opioids
Discuss potential toxicologic adverse effects of therapies associated with COVID-19

Good Intentions but Risky Propositions: Toxicities Associated with Alternative Analgesics
Caitlin Brown

The Collateral Damage of COVID-19: Emerging Toxicities
Megan A Rech

Vaping-Associated Lung Injury: Lessons Learned and Future Implications
Steven Greenberg

Meta Tag

Content Type Presentation

Knowledge Area Pharmacology

Knowledge Area Crisis Management

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Toxicology

Tag Analgesia and Sedation

Tag COVID-19

Year 2021

Keywords

toxicities

alternative analgesics

tramadol

gabapentin

traditional opioids

opioid epidemic

respiratory depression

seizures

antiepileptic drug

opioid-related deaths

	Society of Critical Care Medicine 500 Midway Drive Mount Prospect, IL 60056 USA Phone: +1 847 827-6888 Fax: +1 847 439-7226 Email: support@sccm.org	Contact Us About SCCM Newsroom Advertising & Sponsorship DONATE	MySCCM LearnICU Patients & Families Surviving Sepsis Campaign Critical Care Societies Collaborative	GET OUR NEWSLETTER
© Society of Critical Care Medicine. All rights reserved. \| Privacy Statement \| Terms & Conditions The Society of Critical Care Medicine, SCCM, and Critical Care Congress are registered trademarks of the Society of Critical Care Medicine.