SCCM Resource Library-Glamming Up a GI Bleed

Video Transcription

Video Summary

In this video, Bridget Crum, a clinical pharmacist and professor, discusses the management of upper gastrointestinal (GI) bleeding. She reviews the use of proton pump inhibitors (PPIs) in ulcer upper GI bleed, highlighting that high-dose PPI therapy is associated with improved outcomes. However, the optimal gastric pH target is still unclear. Crum also emphasizes the importance of considering the ethnicity of the patient population, as PPI response may vary between Asian and Western populations. In variceal upper GI bleeding, she discusses the use of antibiotics to prevent infection, and the limited role of PPIs for secondary prophylaxis. Crum also touches on the use of octreotide, a somatostatin analog, in reducing portal pressure, although its overall impact on outcomes is uncertain. Finally, she mentions the use of tranexamic acid, an antifibrinolytic, and concludes that it currently does not have a role in GI bleeding.

Asset Subtitle

GI and Nutrition, Hematology, 2022

Asset Caption

This session will cover new controversies in the medication management of classical disease states, touching base with our critical care roots.

Meta Tag

Content Type Presentation

Knowledge Area Hematology

Knowledge Area GI and Nutrition

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Gastroenterology

Tag Hemorrhage

Year 2022

Keywords

upper gastrointestinal bleeding

proton pump inhibitors

gastric pH target

variceal bleeding

octreotide

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