SCCM Resource Library-Hold the Glucose: Potential Causes of Euglycemic Ketoacidosis

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Video Summary

The presentation covers euglycemic ketoacidosis (euDKA), a variant of diabetic ketoacidosis (DKA) without significant hyperglycemia. Significant attention is given to understanding the causes, symptoms, and management strategies. EuDKA often occurs in patients using sodium-glucose co-transporter-2 (SGLT2) inhibitors, which enhance renal glucose excretion and might lead to reduced insulin use. This condition also arises during continuous renal replacement therapy (CRRT) when glucose-free solutions are used, leading to calorie and glucose deficits.<br /><br />Distinctive symptoms of euDKA include nausea and vomiting, diverging from typical DKA symptoms like severe mental status changes. Managing euDKA involves fluid restoration, insulin administration, and addressing underlying causes like holding SGLT2 inhibitors. Ensuring patients are properly nourished and discontinuing SGLT2 inhibitors pre-surgery or during illness are vital preventative steps. Overall, early diagnosis and intervention are critical to minimize morbidity and mortality connected to euDKA.

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One-Hour Concurrent Session | New Drug, Who's Toxic? New and Emerging Drug Toxicities

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Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

euglycemic ketoacidosis

SGLT2 inhibitors

CRRT

insulin management

preventative steps

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