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Immunomodulation in Perioperative Care
Immunomodulation in Perioperative Care
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Video Transcription
Video Summary
In this video, the speaker discusses the rising threat of microbial resistance and the need for new approaches to combat antibiotic resistance. They introduce the concept of trained immunity, which involves inducing innate immune memory against pathogens. They discuss the use of Toll-like Receptor 4 (TLR4) agonists to induce trained immunity and present two models they have developed and tested using these agonists. The first model focuses on pneumonia, while the second model examines ischemia-reperfusion-induced acute kidney injury. The speaker concludes by emphasizing the potential of trained immunity to enhance antimicrobial functions and preserve organ function, particularly in perioperative medicine.
Asset Subtitle
Immunology, 2023
Asset Caption
Type: two-hour concurrent | Immunomodulation in Critical Illness: A 2023 Update (SessionID 1161720)
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Content Type
Presentation
Knowledge Area
Immunology
Membership Level
Professional
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Tag
Immunology
Year
2023
Keywords
microbial resistance
trained immunity
TLR4 agonists
pneumonia
acute kidney injury
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