SCCM Resource Library-Infectious Diseases: Less Is More

Video Transcription

Video Summary

The 51st Critical Care Congress focused on the Clinical Pharmacy and Pharmacology section's year in review of infectious diseases with the theme of "less is more." One presentation discussed the impact of active anti-pseudomonal beta-lactam use on bacterial resistance to other anti-pseudomonal beta-lactams. The study found that patients with resistance to anti-pseudomonal beta-lactams had a higher 30-day mortality rate and were less likely to be discharged home. The second topic covered the 2021 focused update to the management of Clostridioides difficile infection (CDI). The updated guidelines recommended the use of fidaxomicin over vancomycin as the preferred treatment for the initial episode of CDI, as well as the first recurrence. For patients with recurrent CDI, the guidelines suggested adding bezlotoxumab to the standard antibiotics if they had risk factors for recurrence. The use of fecal microbiota transplant was recommended for patients with two or more recurrences. Limitations of the guidelines include the distinction between recurrence and treatment failure, limited data on bezlotoxumab efficacy when used with fidaxomicin, and the cost consideration of adjunctive therapies.

Asset Subtitle

Pharmacology, Immunology, 2022

Asset Caption

The Society of Critical Care Medicine's Critical Care Congress features internationally renowned faculty and content sessions highlighting the most up-to-date, evidence-based developments in critical care medicine. This is a presentation from the 2022 Critical Care Congress held from April 18-21, 2022.

Meta Tag

Content Type Presentation

Knowledge Area Pharmacology

Knowledge Area Immunology

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Pharmacology

Tag Infectious Diseases

Year 2022

Keywords

Critical Care Congress

Clinical Pharmacy

Pharmacology

infectious diseases

anti-pseudomonal beta-lactam

CDI

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