SCCM Resource Library-Inflammation and the Microbiome: Age-Related Outcomes in the Geriatric Septic Patient

Inflammation and the Microbiome: Age-Related Outcomes in the Geriatric Septic Patient

Video Transcription

Video Summary

The talk addresses sepsis mortality in the elderly, highlighting immunosenescence, inflammation, and the role of microbiome in aging and sepsis. Aging impacts the immune system, leading to weakened responses and increased mortality from sepsis, especially in those over 65. Comorbidities like COPD and diabetes exacerbate these outcomes. The microbiome, aging along with the host, becomes less diverse and more virulent, driving inflammation and worsening sepsis outcomes. Studies indicate that microbiome diversity and virulence significantly influence sepsis results. Conclusively, dysbiosis intensifies sepsis in the elderly, altering microbial composition.

Asset Caption

One-Hour Concurrent Session | The Power of the Microbiome: Its Role in the Development, Maintenance, and Outcomes of Sepsis

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

sepsis

immunosenescence

microbiome

elderly mortality

dysbiosis

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