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Inflammation and the Microbiome: Age-Related Outco ...
Inflammation and the Microbiome: Age-Related Outcomes in the Geriatric Septic Patient
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Video Summary
The talk addresses sepsis mortality in the elderly, highlighting immunosenescence, inflammation, and the role of microbiome in aging and sepsis. Aging impacts the immune system, leading to weakened responses and increased mortality from sepsis, especially in those over 65. Comorbidities like COPD and diabetes exacerbate these outcomes. The microbiome, aging along with the host, becomes less diverse and more virulent, driving inflammation and worsening sepsis outcomes. Studies indicate that microbiome diversity and virulence significantly influence sepsis results. Conclusively, dysbiosis intensifies sepsis in the elderly, altering microbial composition.
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One-Hour Concurrent Session | The Power of the Microbiome: Its Role in the Development, Maintenance, and Outcomes of Sepsis
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Content Type
Presentation
Membership Level
Professional
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Year
2024
Keywords
sepsis
immunosenescence
microbiome
elderly mortality
dysbiosis
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English