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Intrathecal Nicardipine for Post-Subarachnoid Hemo ...
Intrathecal Nicardipine for Post-Subarachnoid Hemorrhage Cerebral Vasospasm: A Pharmacokinetic Study
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Video Summary
The use of intrathecal nicardipine as a treatment for delayed cerebral ischemia in patients with subarachnoid hemorrhage has shown promising results. A study found that delivering nicardipine directly to the affected area was associated with lower rates of delayed cerebral ischemia and improved outcomes. The study also looked at the pharmacokinetics of intrathecal nicardipine and found that there was minimal systemic absorption and that the drug remained in the cerebrospinal fluid at high concentrations. Further studies are needed to validate these findings and determine the optimal dosing and mechanism of action. The results suggest that a clinical trial should be conducted to evaluate the efficacy of this treatment.
Asset Subtitle
Pharmacology, Neuroscience, 2023
Asset Caption
Type: star research | Star Research Presentations: Pharmacology I (SessionID 30015)
Meta Tag
Content Type
Presentation
Knowledge Area
Pharmacology
Knowledge Area
Neuroscience
Membership Level
Professional
Membership Level
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Tag
Calcium Channel Blockers
Tag
Subarachnoid Hemorrhage
Year
2023
Keywords
intrathecal nicardipine
delayed cerebral ischemia
subarachnoid hemorrhage
pharmacokinetics
clinical trial
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