SCCM Resource Library-July Journal Club: Critical Care Medicine (2021)

Video Transcription

Video Summary

In this Journal Club Critical Care Medicine webcast, two articles from Critical Care Medicine were featured. The first presenter, Dr. Elliot Bennett-Guerrero, discussed a randomized trial conducted at Stony Brook Medicine to investigate convalescent plasma as a potential treatment for COVID-19. The trial enrolled hospitalized patients and found that the administration of convalescent plasma increased antibodies to SARS-CoV-2 but did not improve outcomes, including the number of ventilator-free days and mortality. Dr. Bennett-Guerrero highlighted the challenges of conducting the trial during a surge in COVID-19 cases and the need to focus on early treatment in future studies.<br /><br />The second presenter, Dr. Pablo Sanchez, discussed a retrospective cohort study conducted at the University of Pittsburgh Medical Center to compare anticoagulation strategies in patients on veno-veno ECMO for respiratory failure. The study compared heparin to vival as anticoagulation agents and found that vival was associated with a lower rate of in-circuit thrombosis and major bleeding events. The study also found that patients on vival required fewer transfusions of blood products. Dr. Sanchez concluded that the use of vival as an anticoagulation strategy in ECMO patients was beneficial and simplified nursing management.<br /><br />Overall, both studies provided insight into the use of convalescent plasma for COVID-19 and anticoagulation strategies in ECMO patients.

Asset Subtitle

Research, Infection, 2021

Asset Caption

"The Journal Club: Critical Care Medicine webcast series focuses on articles of interest from Critical Care Medicine.

This series is held on the fourth Thursday of each month and features in-depth presentations and lively discussion by the authors.

Follow the conversation at #CritCareMed."

Meta Tag

Content Type Webcast

Knowledge Area Research

Knowledge Area Infection

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Professional

Membership Level Associate

Membership Level Select

Tag Outcomes Research

Tag COVID-19

Year 2021

Keywords

convalescent plasma

COVID-19

randomized trial

SARS-CoV-2

ventilator-free days

mortality

anticoagulation strategies

veno-veno ECMO

respiratory failure

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