SCCM Resource Library-June Journal Club Webcast: Spotlight on Pharmacy (2020)

Video Transcription

Video Summary

Today's Journal Club Spotlight focused on three different studies related to critical care medicine. The first study discussed the use of prothrombin-complex concentrates (PCC) as a treatment for patients with Factor Xa inhibitor-related intracranial hemorrhage. The study found that PCCs were effective in achieving hemostasis and had low rates of thrombosis. However, the study acknowledged the limitations of its retrospective design and the need for further research, particularly in comparing PCCs to target-specific reversal agents like andexanet-alpha.<br /><br />The second study examined the use of early enteral antihypertensives in patients with hypertensive intracranial hemorrhage. The study found that early initiation of oral antihypertensives reduced ICU length of stay and hospital costs without increasing the risk of hypotension. The authors recommended the development of a standardized approach to blood pressure management in this patient population.<br /><br />The final study focused on medication safety during hyperglycemic emergencies, specifically diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). The study compared high-intensity insulin therapy with moderate-intensity therapy and found that moderate-intensity therapy reduced hospital length of stay and the prevalence of hypoglycemia. The authors suggested that the 2009 American Diabetes Association guidelines should be revised to promote patient safety.<br /><br />Overall, these studies highlight the importance of evidence-based approaches to patient care in critical care settings and the need for further research to optimize treatment strategies.

Asset Subtitle

Pharmacology, Neuroscience, 2020

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Neuroscience

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Pharmacology

Tag Neurology

Year 2020

Keywords

critical care medicine

prothrombin-complex concentrates

Factor Xa inhibitor-related intracranial hemorrhage

hemostasis

thrombosis

retrospective design

early enteral antihypertensives

hypertensive intracranial hemorrhage

ICU length of stay

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