SCCM Resource Library-June Journal Club Webcast: Spotlight on Pharmacy (2021)

Video Transcription

Video Summary

In this Journal Club Spotlight on Pharmacy webcast, three presenters discussed different articles related to critical care pharmacy. The first presenter discussed therapeutic anticoagulation in critically ill patients with COVID-19. They explained that hypercoagulability in COVID-19 is caused by dysregulated immune response, leading to inflammation and activation of the coagulation cascade. While thromboembolic events are more common in ICU patients with COVID-19, therapeutic anticoagulation did not improve outcomes in severe COVID-19 patients. The second presenter discussed the inappropriate continuation of antipsychotics in ICU delirium during transitions of care. They found that 52% of antipsychotics were continued after ICU discharge, and longer ICU length of stay was associated with a lower risk of continuation. The authors recommended caution in care transitions to prevent unnecessary medication exposure. The third presenter discussed the use of phenylephrine push before continuous infusion of norepinephrine in septic shock. They found that phenylephrine push was associated with early but not sustained hemodynamic stability. Longer ICU length of stay was a protective factor against continuation of phenylephrine at hospital discharge. They cautioned against the use of phenylephrine push before norepinephrine initiation in hemodynamically unstable septic shock patients. Overall, these presentations shed light on important topics in critical care pharmacy and provided valuable insights for clinical practice.

Asset Subtitle

Pharmacology, Infection, 2021

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Infection

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Anticoagulation

Tag COVID-19

Year 2021

Keywords

critical care pharmacy

therapeutic anticoagulation

COVID-19

ICU patients

antipsychotics

ICU delirium

transitions of care

phenylephrine push

septic shock

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