SCCM Resource Library-June Journal Club Webcast: Spotlight on Pharmacy (2022)

Video Transcription

Video Summary

The Journal Club Spotlight on Pharmacy webcast discussed three articles related to critical care pharmacy. The first article focused on the hemodynamic effects of ketamine compared to propofol or dexmedetomidine as continuous ICU sedation. The study found that ketamine was associated with less hypotension and bradycardia compared to the other sedative agents. The second article examined the use of subcutaneous insulin protocol for diabetic ketoacidosis (DKA) management. The study found that the use of subcutaneous insulin was safe and associated with better outcomes, including a reduction in ICU admissions and 30-day readmissions. The third article compared the use of direct oral anticoagulants (DOACs) to warfarin in the treatment of cerebral venous thrombosis (CVT) . The study found that DOACs were a reasonable alternative to warfarin in patients with CVT, with comparable efficacy and a potentially lower risk of major hemorrhage. Overall, the findings of these studies provide valuable insights for critical care pharmacists and suggest potential changes in practice for sedation and anticoagulation management.

Asset Subtitle

Pharmacology, Neuroscience, 2022

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Tyler Brouse, PharmD
Atchley E, Tesoro E, Meyer R, Bauer A, Pulver M, Benken S. Hemodynamic effects of ketamine compared with propofol or dexmedetomidine as continuous ICU sedation. Ann Pharmacother. 2022 Jul;56(7):764-772.

Michael Young, PharmD, BCPS
Rao P, Jiang SF, Kipnis, et al. Evaluation of outcomes following hospital-wide implementation of a subcutaneous insulin protocol for diabetic ketoacidosis. JAMA Netw Open. 2022 Apr 1;5(4):e226417.

Clare Cycz, PharmD
Yaghi S, Shu L, Bakradze E, et al. Direct oral anticoagulants versus warfarin in the treatment of cerebral venous thrombosis (ACTION-CVT): a multicenter international study. Stroke. 2022 Mar;53(3):728-738.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Neuroscience

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Tag Analgesia and Sedation

Tag Diabetes

Tag Anticoagulation

Year 2022

Keywords

critical care pharmacy

ketamine

propofol

dexmedetomidine

subcutaneous insulin protocol

diabetic ketoacidosis

DOACs

warfarin

cerebral venous thrombosis

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