SCCM Resource Library-Late-Breaking Studies Affecting Patient Outcomes II

Video Transcription

Video Summary

This session highlighted four significant presentations impacting patient outcomes in critical care:<br /><br />1. Dr. Lars Palmowski presented research on the "Timely Cessation of Proton Pump Inhibitors in Critically Ill Patients." The study revealed that unnecessary PPI continuation post-discharge increased morbidity, re-hospitalization (by 35%), and mortality (by 17%).<br /><br />2. Dr. Gayan Kayaster discussed the reduction of antibiotic duration for ventilator-associated pneumonia (VAP) through the RIGAV-BAP trial. The trial indicated that short-course antibiotic treatments were non-inferior to longer treatments, reducing side effects, antibiotic use, and costs, especially in low-income settings.<br /><br />3. Dr. Nazima Pathan presented the pediatric arm of the recovery trial for PIMS-TS associated with COVID-19. Findings suggested methylprednisolone significantly reduced hospital stay and inflammation compared to IVIG. In severe cases, tocilizumab showed potential benefit but increased the need for inotropes.<br /><br />4. Dr. Loren Schlappach shared results from a pilot study on metabolic resuscitation using vitamin C, thiamine, and hydrocortisone in children with septic shock. The study demonstrated feasibility in implementing such trials, with promising results for metabolic adjunctive therapies, despite some methodological challenges.<br /><br />Overall, these studies emphasize the need for targeted interventions in critical care to improve both efficacy and safety of patient treatments.

Asset Caption

One-Hour Concurrent Session | Late-Breaking Studies Affecting Patient Outcomes II

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

critical care

patient outcomes

proton pump inhibitors

ventilator-associated pneumonia

antibiotic duration

PIMS-TS

metabolic resuscitation

COVID-19

pediatric trials

	Society of Critical Care Medicine 500 Midway Drive Mount Prospect, IL 60056 USA Phone: +1 847 827-6888 Fax: +1 847 439-7226 Email: support@sccm.org	Contact Us About SCCM Newsroom Advertising & Sponsorship DONATE	MySCCM LearnICU Patients & Families Surviving Sepsis Campaign Critical Care Societies Collaborative	GET OUR NEWSLETTER
© Society of Critical Care Medicine. All rights reserved. \| Privacy Statement \| Terms & Conditions The Society of Critical Care Medicine, SCCM, and Critical Care Congress are registered trademarks of the Society of Critical Care Medicine.