SCCM Resource Library-Late-Breaking Studies That Will Change Your Practice (William C. Shoemaker Memorial Lecture)

Late-Breaking Studies That Will Change Your Practice (William C. Shoemaker Memorial Lecture)

Video Transcription

Video Summary

Dr. Ram Narayan, a pediatric intensivist from London, discusses the results of the first ABC trial in children. The trial compared high-flow nasal cannula with continuous positive airway pressure (CPAP) for post-extubation respiratory support. This trial is the first randomized controlled trial comparing the two interventions in children. The trial involved 600 patients who were randomized to receive either high-flow nasal cannula or CPAP. The primary outcome of the trial was time to liberation from all forms of respiratory support. The results showed that high-flow nasal cannula did not meet the non-inferiority criterion compared to CPAP in terms of time to liberation. However, there were no significant differences in key secondary outcomes such as reintubation rates, patient comfort, and parental stress. The findings highlight the need for more protocolized approaches to post-extubation respiratory support in children.

Asset Subtitle

Quality and Patient Safety, 2022

Asset Caption

The Society of Critical Care Medicine's Critical Care Congress features internationally renowned faculty and content sessions highlighting the most up-to-date, evidence-based developments in critical care medicine. This is a presentation from the 2022 Critical Care Congress held from April 18-21, 2022.

Meta Tag

Content Type Presentation

Knowledge Area Quality and Patient Safety

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Evidence Based Medicine

Tag Updates and Future Directions

Year 2022

Keywords

ABC trial

high-flow nasal cannula

CPAP

respiratory support

randomized controlled trial

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