This article was first published in the Winter 2022 issue of Critical Connections. In populations hardest hit by COVID-19, innovative healthcare and community professionals created paradigm shifts to battle healthcare access limitations, distrust of the healthcare system, and healthcare literacy disparities in the new age of physical distancing. Here we identify some best practices and examples of organizations and healthcare leaders working to mitigate barriers to quality care for racial and ethnic minorities. Critical Connections, the critical care industry's only newsmagazine, provides information on cutting-edge topics in critical care useful to the entire multiprofessional team. Authors: Samantha Gambles Farr, MSN, FNP-C, CCRN, RNFA Nadia Ferguson, PharmD, BCPS, BCCCP Ramon E. Gist, MD, FAAP