SCCM Resource Library-Less is More: Neuromuscular Blocking Agents

Video Transcription

Video Summary

Kayla Nichols, a CVIC pharmacist at Emory University Hospital in Atlanta, discusses the use of neuromuscular blocking agents (NMBAs) in ARDS (acute respiratory distress syndrome). She reviews the criteria for diagnosing ARDS and the progression of the disease. Nichols then examines the literature on the benefits of NMBAs, including improved oxygenation, reduced inflammation, and decreased mortality. She highlights two studies, AcuraSys and ROSE, which assess the effect of NMBAs on mortality in ARDS patients. Ultimately, Nichols concludes that the use of NMBAs may be beneficial in severe ARDS cases requiring deep sedation within the first 48 hours, but not in milder cases.

Asset Subtitle

Procedures, Quality and Patient Safety, 2022

Asset Caption

This session will explore when less intervention means better outcomes in mechanical ventilation. The session will be centered around less use of muscle relaxants (ROSE trial), less use of extracorporeal carbon dioxide removal (REST trial) and less use of fluids.

Meta Tag

Content Type Presentation

Knowledge Area Procedures

Knowledge Area Quality and Patient Safety

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Tag Mechanical Ventilation

Tag Evidence Based Medicine

Year 2022

Keywords

ARDS

NMBAs

oxygenation

inflammation

mortality

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