SCCM Resource Library-Making the Most of the Clinical Toolbox: Improving Outcomes in HABP and VABP

Video Transcription

Video Summary

The video titled "Making the Most of the Clinical Toolbox" discusses the importance of appropriate antibiotic therapy in the treatment of nosocomial pneumonia. The speakers highlight the increasing incidence of pneumonia in hospitals, particularly among immunocompromised patients and those receiving certain treatments. They emphasize the need for rapid diagnostic tests to guide empirical treatment and provide real-time data on antibiotic susceptibility. The video also mentions new antibiotics available for pneumonia treatment, such as ceftolizumab plus tezobactam and ceftazidime/avibactam, which offer improved coverage against resistant pathogens. The speakers stress the importance of personalized antibiotic dosing in critically ill patients. The video also discusses the use of new cephalosporin beta-lactamase inhibitors for difficult-to-treat gram-negative pathogens and highlights other drugs on the market, such as mirapenem-vabbactam and schofittraco, for treating specific infections. The video emphasizes the need for individualized therapy and a multidisciplinary approach, taking into account factors such as prior antibiotic exposure, immune status, comorbidities, and resistance patterns. Rapid diagnostic tests and responsible antibiotic use are also emphasized. The video concludes by addressing questions on specific aspects of treatment. Overall, the video advocates for the optimal use of antibiotics to improve outcomes in patients with nosocomial pneumonia and ventilator-associated pneumonia.

Asset Subtitle

Infection, Quality and Patient Safety, 2020

Asset Caption

The Society of Critical Care Medicine's Critical Care Congress features internationally renowned faculty and content sessions highlighting the most up-to-date, evidence-based developments in critical care medicine. This is a presentation from the 2020 Critical Care Congress held February 16-19, 2020, in Orlando, Florida, USA.

This program is supported by an educational grant from Merck & Co., Inc.

Learning Objectives

Explain the evolving epidemiology and etiology of hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP)
Discuss key safety and efficacy data for newer agents being used for the treatment of HABP and VABP
Develop tailored treatment strategies for HABP and/or VABP that support the principles of antibiotic stewardship
Coordinate with members of the multiprofessional care team to improve timely diagnoses

Welcome and Introductions

Marin H. Kollef

HABP and VABP: Epidemiology, Microbiology, and Clinical Consequences

Richard Wunderink

Considerations for Antiobiotic Therapy for MDR Infections in HABP and VABP

Debra Goff

New and Emerging Therapies: A Closer Look at the Data

Richard Wunderink

Individualizing Therapy to Support Antimicrobial Stewardship and Improved Outcomes

Marin Kollef

Concluding Remarks and Audience Q&A

Marin Kollef

Meta Tag

Content Type Presentation

Knowledge Area Quality and Patient Safety

Knowledge Area Infection

Knowledge Level Foundational

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Guidelines

Tag Mortality

Year 2020

Keywords

appropriate antibiotic therapy

nosocomial pneumonia

rapid diagnostic tests

new antibiotics

ceftolizumab plus tezobactam

ceftazidime/avibactam

personalized antibiotic dosing

gram-negative pathogens

individualized therapy

responsible antibiotic use

improve outcomes

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