SCCM Resource Library-Management of Adult Acute and Acute-on-Chronic Liver Failure

Management of Adult Acute and Acute-on-Chronic Liver Failure

Video Transcription

Video Summary

The presentation covers neurologic considerations in acute liver failure (ALF) and acute-on-chronic liver failure (ACLF). Key points include recommendations against using invasive intracranial monitoring in ALF due to safety concerns, and the utility of plasma exchange in managing hyperammonemia. High-dose CRRT is highlighted for its increasing role in ALF management. The use of hypertonic saline is suggested for intracranial hypertension, while induced hypothermia is not recommended. In ACLF, lactulose and polyethylene glycol are advised for hepatic encephalopathy, with rifaximin as an adjunct. Broad-spectrum antibiotics and antifungal prophylaxis are recommended for infection management and prevention.

Asset Caption

One-Hour Concurrent Session | New SCCM Guidelines: Liver Failure, New Fever, and Corticosteroids

Meta Tag

Content Type Presentation

Membership Level Professional

Membership Level Select

Year 2024

Keywords

acute liver failure

intracranial monitoring

plasma exchange

hepatic encephalopathy

infection management

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