SCCM Resource Library-March Journal Club: Critical Care Medicine (2021)

Video Transcription

Video Summary

In this Journal Club Critical Care Medicine webcast, two presenters, Dr. Erika Plata and Dr. Ryan Mays, discuss the use of procalcitonin (PCT) guidance in critically ill patients with sepsis. Dr. Plata presents the viewpoint supporting the use of PCT guidance, while Dr. Mays provides the counter-argument. Dr. Plata emphasizes the importance of early recognition and treatment of sepsis, as well as the need to reduce exposure to broad-spectrum antibiotics in order to combat antimicrobial resistance. She explains that PCT is a biomarker that can provide objective data in addition to clinical assessments when making antibiotic treatment decisions. Several studies have shown that PCT-guided algorithms can be effective and safe for de-escalating antibiotics, leading to shorter durations of therapy without adversely affecting outcomes. Dr. Plata also highlights the need for education and implementation of evidence-based algorithms for the successful use of PCT guidance. On the other hand, Dr. Mays raises concerns about the potential misinterpretation of PCT levels and the overreliance on biomarkers rather than evidence-based durations of antibiotic therapy. He argues that while PCT can be a useful tool, it should not replace clinical assessments and should be used in conjunction with evidence-based guidelines for antibiotic therapy. Both presenters agree that further research and data are needed to fully understand the role of PCT in guiding antibiotic therapy in different populations and clinical scenarios. Overall, this webcast provides a comprehensive overview of the use of PCT guidance in critically ill patients with sepsis, highlighting its potential benefits and limitations.

Asset Subtitle

Pharmacology, Sepsis, 2021

Asset Caption

"The Journal Club: Critical Care Medicine webcast series focuses on articles of interest from Critical Care Medicine.

This series is held on the fourth Thursday of each month and features in-depth presentations and lively discussion by the authors.

Follow the conversation at #CritCareMed."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Sepsis

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Pharmacology

Tag Sepsis

Year 2021

Keywords

Journal Club Critical Care Medicine

procalcitonin guidance

critically ill patients

sepsis

early recognition

treatment of sepsis

antimicrobial resistance

PCT biomarker

antibiotic treatment decisions

PCT-guided algorithms

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