SCCM Resource Library-March Journal Club: Spotlight on Pharmacy (2023)

Video Transcription

Video Summary

This journal club spotlight on pharmacy webcast focused on three different studies. The first study compared teclaplace versus alteplase in acute ischemic cerebrovascular events. The researchers found that teclaplace was non-inferior to alteplase for the treatment of stroke within 4.5 hours of symptom onset. The second study looked at early restrictive or liberal fluid management for sepsis-induced hypotension. The researchers found that there was no difference in mortality between the restrictive and liberal fluid strategies. The third study compared amiodarone and lidocaine for the treatment of in-hospital cardiac arrest. The researchers found that lidocaine had a higher rate of 24-hour survival, survival to hospital discharge, and favorable neurological outcomes compared to amiodarone. Overall, these studies provide new insights into the treatment of stroke, sepsis-induced hypotension, and in-hospital cardiac arrest. They suggest that teclaplace may be a viable alternative to alteplase for stroke patients, that fluid strategy may not impact mortality in sepsis-induced hypotension, and that lidocaine may be a preferred agent for in-hospital cardiac arrest compared to amiodarone.

Asset Subtitle

Neuroscience, Pharmacology, Sepsis, 2023

Asset Caption

The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research. Registered attendees receive complimentary access to the webcast for one year.

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Neuroscience

Knowledge Area Sepsis

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Tag Sepsis

Tag Anticoagulation

Tag Stroke

Year 2023

Keywords

journal club spotlight

pharmacy webcast

teclaplace

alteplase

stroke

fluid management

sepsis-induced hypotension

amiodarone

lidocaine

in-hospital cardiac arrest

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