SCCM Resource Library-March Journal Club: Spotlight on Pharmacy (2025)

Video Transcription

Video Summary

The Journal Club Spotlight on Pharmacy webcast, supported by the Society of Critical Care Medicine, featured presentations by three PGY-2 critical care pharmacy residents. Kayla Kahn from Memorial Hermann discussed the BALANCE trial, exploring whether a 7-day antibiotic treatment for bloodstream infections is non-inferior to a 14-day regimen concerning 90-day mortality. Her findings suggested that seven days could be sufficient, but emphasized the importance of patient evaluation. Natalia Smith from the University of Maryland reviewed the PROTECTION trial, assessing whether intravenous amino acids could reduce acute kidney injury in post-cardiac surgery patients. Results indicated amino acid therapy reduced AKI rates, mainly impacting stage one AKI, but lacked significant patient-centered outcome benefits. Angela Castro from UC San Diego focused on the PROACTIVE trial, examining propranolol's sedative-sparing effects in mechanically ventilated ICU patients. The study showed a reduction in sedative needs by propranolol, but its clinical significance remains uncertain, prompting calls for further research. Overall, these presentations introduced potential therapeutic strategies but highlighted the need for patient-specific application and further investigation.

Asset Subtitle

Pharmacy, Renal. Neuroscience, 2025

Asset Caption

The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research. Registered attendees receive complimentary access to the webcast for one year.

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Renal

Knowledge Area Neuroscience

Membership Level Professional

Membership Level Select

Tag Antibiotics

Tag Renal

Tag Analgesia and Sedation

Year 2025

Keywords

Webcast

Pharmacology

Renal

Neuroscience

2025

Antibiotics

Analgesia and Sedation

Professional

Select

critical care pharmacy

antibiotic treatment

bloodstream infections

acute kidney injury

amino acid therapy

mechanically ventilated ICU

propranolol

therapeutic strategies

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