SCCM Resource Library-March Journal Club Webcast: Spotlight on Pharmacy (2020)

Video Transcription

Video Summary

The Journal Club Spotlight on Pharmacy webcast discussed three different studies. The first study, called the PEPTIC trial, compared the use of proton pump inhibitors (PPIs) versus histamine 2 receptor blockers (H2R blockers) for stress ulcer prophylaxis in ICU patients receiving mechanical ventilation. The study found that the use of PPIs was associated with a higher in-hospital mortality compared to H2R blockers, although the difference was not statistically significant. The second study, called the DEXA ARDS trial, looked at the use of early dexamethasone treatment in patients with acute respiratory distress syndrome (ARDS). The study found that early administration of dexamethasone did not reduce 90-day mortality in ICU patients with ARDS. The third study, called the 65 trial, investigated the effect of decreased exposure to vasopressors on 90-day mortality in elderly patients. The study found that targeting a mean arterial pressure (MAP) of 60 to 65 in elderly patients with vasodilatory hypotension did not reduce 90-day mortality compared to usual care. Overall, these studies provide important insights into the management of critically ill patients and highlight the need for further research in specific patient populations.

Asset Subtitle

Pharmacology, GI and Nutrition, Research, 2020

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area GI and Nutrition

Knowledge Area Research

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Pharmacology

Tag Gastroenterology

Tag Evidence Based Medicine

Year 2020

Keywords

PEPTIC trial

proton pump inhibitors

H2R blockers

stress ulcer prophylaxis

DEXA ARDS trial

dexamethasone treatment

acute respiratory distress syndrome

65 trial

vasopressors

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