SCCM Resource Library-March Journal Club Webcast: Spotlight on Pharmacy (2021)

Video Transcription

Video Summary

The Journal Club discussed three different topics related to critical care pharmacy. The first presentation focused on sedation in critically ill patients and compared the use of propofol and dexmedetomidine. The presenter reviewed the literature on both agents and discussed the potential benefits and limitations of each. The main conclusion was that there is no clear preference between the two agents and that future research is needed with higher doses and longer duration of the study drug. The second presentation examined the use of interleukin-6 receptor antagonists in critically ill patients with COVID-19. The presenter discussed the mixed results from previous studies and highlighted the recent REMAP-CAP trial, which showed a benefit in terms of mortality and ventilator-free days for patients receiving tocilizumab or serolamab. The presenter suggested considering the use of these agents in conjunction with glucocorticoids for severely ill COVID-19 patients. The third presentation looked at the use of phenylefrine in septic shock patients with atrial fibrillation. The presenter discussed a retrospective cohort study that compared phenylefrine to norepinephrine and found no difference in sustained heart rate control between the two agents. The presenter concluded that further research is needed with larger, prospective, and controlled trials to determine the true effect of phenylefrine on rate control in this patient population. Overall, the presentations highlighted the current state of the literature on these topics and underscored the need for more research in the field of critical care pharmacy.

Asset Subtitle

Pharmacology, 2021

Asset Caption

"The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research.

Follow the conversation at #SCCMCPPJC."

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Level Intermediate

Knowledge Level Advanced

Membership Level Select

Membership Level Professional

Membership Level Associate

Tag Analgesia and Sedation

Year 2021

Keywords

Journal Club

critical care pharmacy

sedation

propofol

dexmedetomidine

interleukin-6 receptor antagonists

COVID-19

tocilizumab

serolamab

phenylephrine

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