SCCM Resource Library-May Journal Club: Spotlight on Pharmacy (2023)

Video Transcription

Video Summary

In today's Journal Club Spotlight on Pharmacy webcast, three presentations were given on different topics in pharmacy. The first presenter discussed a randomized trial comparing bivalirudin plus a high-dose infusion to heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The trial found that bivalirudin reduced bleeding events without increasing the risk of major adverse cardiac events or stent thrombosis compared to heparin. The second presenter discussed a comparison of four-factor prothrombin complex concentrate and indexanet alfa for reversal of pixaban and ribavirin in the setting of intracranial hemorrhage. The trial found no significant difference between the two agents in terms of mortality, major bleeding, or stent thrombosis. The third presenter discussed a trial of nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery. The trial found that dexmedetomidine reduced the risk of delirium on post-op day one, but the effect was not maintained on post-op day three. Overall, the presentations highlighted the importance of considering different anticoagulant and reversal agents in specific patient populations, as well as the need for further research in the field of delirium prevention.

Asset Subtitle

Pharmacology, Cardiovascular, Neuroscience, 2023

Asset Caption

The Journal Club: Spotlight on Pharmacy webcast series focuses on pharmacy topics. This event is held on the third Friday of each month and features lively discussion and in-depth presentations on the latest research. Registered attendees receive complimentary access to the webcast for one year.

Meta Tag

Content Type Webcast

Knowledge Area Pharmacology

Knowledge Area Cardiovascular

Knowledge Area Neuroscience

Knowledge Level Advanced

Learning Pathway Cardiothoracic Critical Care

Membership Level Professional

Membership Level Select

Tag Cardiothoracic Critical Care

Tag Myocardial Ischemia and Reperfusion

Tag Anticoagulation

Tag Delirium

Year 2023

Keywords

Journal Club Spotlight

Pharmacy webcast

randomized trial

bivalirudin

heparin monotherapy

ST-segment elevation myocardial infarction

reversal

intracranial hemorrhage

delirium prevention

cardiac surgery

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