SCCM Resource Library-Molecular Measurements in SARI-PREP

Video Transcription

Video Summary

In this video, Dr. Pavan Bhattacharya discusses the SariPrep study, a multicenter prospective study that aims to understand severe acute respiratory infection (SARI), including COVID-19, and other viral infections. The study involves the collection of various biospecimens from enrolled patients, such as plasma, urine, blood, and swabs, to perform molecular measurements and analyses. Dr. Bhattacharya highlights the proteomics analysis conducted using the Somascan platform, which identified proteins associated with ventilator-free days and poor outcomes in COVID-19 patients. The study also found a potential drug target, angiopoietin-like 4 (AngPTL4), which has been implicated in other viral infections. The SariPrep study is ongoing with enrollment still ongoing for different respiratory viruses.

Asset Subtitle

Sepsis, Quality and Patient Safety, 2023

Asset Caption

Type: one-hour concurrent | SARI-PREP: Outcomes From a Multicenter Consortium (SessionID 9999901)

Meta Tag

Content Type Presentation

Knowledge Area Sepsis

Knowledge Area Quality and Patient Safety

Membership Level Professional

Membership Level Select

Tag Guidelines

Tag Sepsis

Year 2023

Keywords

SariPrep study

severe acute respiratory infection

COVID-19

proteomics analysis

AngPTL4

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